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TRIHEXYPHENIDIL


TRIHEXYPHENIDYL

Trihexyphenidyl (Artane, Apo-Trihex), also known as benzhexol, is an antiparkinsonian agent of the antimuscarinic class. It has been in clinical usage for decades. The drug is available as the hydrochloride salt.

 
 
Systematic (IUPAC) name
(RS)-1-cyclohexyl-1-phenyl-
3-(1-piperidyl)propan-1-ol

Clinical data
AHFS/Drugs.com : monograph
MedlinePlus : a682160
Pregnancy cat. : C US
Legal status : Rx-Only (US)
Routes : Oral, as tablet or elixir
Pharmacokinetic data
Half-life : 3.3-4.1 hours
Identifiers
CAS number : 144-11-6
ATC code : N04AA01
PubChem : CID 5572
DrugBank : DB00376
ChemSpider  : 5371
UNII : 6RC5V8B7PO
KEGG : D08638
ChEMBL : CHEMBL1490
Chemical data
Formula : C20H31NO
Mol. Mass : 301.466 g/mol
SMILES : OC(c1ccccc1)(CCN2CCCCC2)C3CCCCC3
InChI : InChI=1S/C20H31NO
/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21
/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2
Key:HWHLPVGTWGOCJO-UHFFFAOYSA-N

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