What I Want to Know???....

Dextromethorphan

Dextromethorphan (DXM or DM) is an antitussive (cough suppressant) drug. It is one of the active ingredients in many over-the-counter cold and cough medicines, such as Mucinex DM, Robitussin, NyQuil, Dimetapp, Vicks, Coricidin, Delsym, and others, including generic labels. Dextromethorphan has also found other uses in medicine, ranging from pain relief to psychological applications. It is sold in syrup, tablet, spray, and lozenge forms. In its pure form, dextromethorphan occurs as a white powder.

 

 

Systematic (IUPAC) name

(+)-3-methoxy-17-methyl-(9α,13α,14α)-morphinan

Clinical data

Trade names : Delsym

AHFS/Drugs.com : monograph

MedlinePlus : a682492

Pregnancy cat. : A (AU) C (US)

Legal status : Pharmacy Only (S2) (AU) OTC (US)

Routes : Oral

Pharmacokinetic data

Bioavailability : 11%

Metabolism : Hepatic (liver) enzymes: major CYP2D6, minor CYP3A4, and minor CYP3A5

Half-life : 1.4–3.9 hours

Excretion : Renal

Identifiers

CAS number : 125-71-3

ATC code : R05DA09

PubChem : CID 15978238

DrugBank : DB00514

ChemSpider : 13109865

UNII : 7355X3ROTS

KEGG : D03742

ChEMBL : CHEMBL52440

Chemical data

Formula : C₁₈H₂₅NO

Mol. Mass : 271.4 g/mol

SMILES : O(c1ccc3c(c1)[C@@]24[C@@H]([C@H](N(CC2)C)C3)CCCC4)C

InChI : InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18

/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1

Key:MKXZASYAUGDDCJ-NJAFHUGGSA-N

Physical data

Melt. Point : 111 °C (232 °F)

Source : http://en.wikipedia.org/wiki/Dextromethorphan